Month: December 2022

Liked on YouTube: Cholesterol Metabolism, LDL, HDL and other Lipoproteins, Animation

(USMLE topics) The science behind the GOOD and BAD cholesterol. Cholesterol transport and pathways, drugs used for treatment of atherosclerosis.
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Despite having a BAD reputation as a high-risk factor for cardiovascular diseases, cholesterol is an ESSENTIAL component of all animal cells. It is an INTEGRAL part of the cell membrane, providing membrane FLUIDITY and participating in a number of cellular processes. Cholesterol also serves as a PRECURSOR for production of bile, steroid hormones, and vitamin D. While the body can obtain cholesterol from food, many cells SYNTHESIZE their own ENDOGENOUS cholesterol. Cellular production of cholesterol is under NEGATIVE FEEDBACK control. LOW levels of intracellular cholesterol INDUCE its own production, while HIGH cholesterol levels INHIBIT it.
Cholesterol, together with other lipids, is transported in blood plasma within large particles known as LIPOPROTEINS. A lipoprotein is an assembly of lipids and proteins. Lipoproteins are classified based on their DENSITY. Because lipids are LIGHTER than proteins, particles that contain MORE lipids are LARGER in size but have LOWER density. Different types of lipoproteins have different sets of proteins on their surface. These proteins serve as “ADDRESS tags”, determining the DESTINATION, and hence FUNCTION, of each lipoprotein. For example, LOW-density lipoprotein, LDL, carries cholesterol FROM the liver to other tissues, while HIGH-density lipoprotein, HDL, RETURNS excess cholesterol TO the liver.
Major events in cholesterol metabolism include:
– Dietary cholesterol ABSORBED in the intestine and carried in chylomicron to the liver.
– The liver PACKAGES its cholesterol pool – a combination of endogenous and dietary – together with triglycerides, another type of lipid, into particles of VERY-LOW-density lipoprotein, VLDL.
– VLDL travels in bloodstream to other organs. During circulation, muscle and adipose tissues EXTRACT triglycerides from VLDL, turning it into LOW-density lipoprotein, LDL.
– Peripheral cells TAKE UP LDL by endocytosis, using LDL receptor. Cholesterol is used in cell membrane and other functions.
– EXCESS cholesterol is exported from the cells and delivered to HIGH-density lipoprotein, HDL, to be RETURNED to the liver in a process called REVERSE cholesterol transport.
– The liver uses cholesterol to produce BILE; bile is secreted to the intestine, where it helps break down fats. Part of this bile is EXCRETED in feces; the rest is RECYCLED back to the liver.
LDL has the highest cholesterol content and is the MAJOR carrier of cholesterol in the blood. High levels of LDL in the blood are associated with cholesterol plaque build-up and cardiovascular diseases such as heart attacks and strokes. For this reason, LDL is known as “BAD” cholesterol. On the other hand, HDL is called “GOOD” cholesterol, because it REMOVES EXCESS cholesterol from tissues and bloodstream.
Common drugs used to LOWER cholesterol include: INHIBITORS of endogenous cholesterol PRODUCTION; INHIBITORS of intestinal cholesterol ABSORPTION; and INHIBITORS of bile reuptake.

Liked on YouTube: Is someone tracking you WITHOUT your knowledge? Look for these 5 signs: 😱

oh oh! Your location, conversations, private text messages, video recordings, Snapchat, and tinder messages are being shared. With so many spy apps easily available, more people are discovering that their phone is spying on them. Usually, this is installed by an ex, or the spouse, or even by someone from work. These apps are sneaky and hide on your phone so you wouldn’t even know they were there.
So here are 5 signs that your phone is being tracked with spy apps and how to clean your phone to remove the spy apps.

How to track anyone’s phone location without them knowing: https://youtu.be/ZQGhtHflaAM

Secret phone codes can spy on you without your knowledge!: https://www.youtube.com/watch?v=F4eMfvpCHF8

0:00 5 signs someone is RECORDING you
1:00 Tracking your OWN phone (Android and iPhone)
3:00 How do you know Spy Apps are running
5:00 How to remove Spy Apps

#TheTechieGuy
Need to get faster wifi and faster internet? Is your gaming lagging and your zoom buffering? Whats a Mesh WiFi and WiFi 6 anyways? Don’t worry – I got you.
Here is where I show you all you need to know about faster and better connectivity with best router settings, wifi optimization, wifi tips and internet bandwidth performance tricks and even boosting speed apps.
If you also want to know about which phone you should buy, I got that for you too!
The latest Samsung Galaxy S9, S20 Ultra, Galaxy Note 10, or Google Pixel 4 XL? or perhaps the Apple iPhone 11 vs OnePlus Pro? If you also want to know the best cell tips and tricks then you are definitely in the right place!

My name is Liron Segev, aka TheTechieGuy, and I make tech simple for everyone to understand – I answer your technology questions making so you are more productive more efficient and getting more out of your phones, gadgets, and apps

Liron Segev aka TheTechieGuy
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Liked on YouTube: Switch off your phone’s WiFi now!

Do you have your WiFi’s phone switched on even when you leave your home or work? That is a BIG mistake!

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#TheTechieGuy
Need to get faster wifi and faster internet? Is your gaming lagging and your zoom buffering? What is a Mesh WiFi and WiFi 6?
I show you all you need to know about faster and better connectivity with the best router settings, wifi optimization, wifi tips and internet bandwidth performance tricks and even boosting speed apps.

My name is Liron Segev, aka TheTechieGuy, and I make tech simple for everyone to understand – I answer your technology questions making so you are more productive more efficient, and getting more out of your phones, gadgets, and apps

Liron Segev aka TheTechieGuy
https://ift.tt/GvjsXBJ

FYI: As an Amazon Associate I earn from qualifying purchases

Liked on YouTube: Europe’s First Big Move to Punish USA Causes Uproar Among American Energy Giants | EU Exxon Mobil

Europe’s First Big Move to Punish USA Causes Uproar Among American Energy Giants | EU Exxon Mobil
Russia’s war in Ukraine did have a winner this year – American oil and gas companies. These giants amassed billions of dollars thanks to global supply chain disruptions and soaring prices. It was obvious that governments wouldn’t let this party on for long, without getting a share for itself. With this intention, the European Union began taxing energy companies on the profits they made. And now, the bloc is facing the ire of one such US-based company which has sued them for these new taxes. Washington’s presence has just heightened the possibility of the much-discussed EU-US trade war.

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Europe | European Union | US | US EU Trade War | Exxon | ExxonMobil | Exxon EU Windfall Tax | Europe Oil & Gas | Russian Oil | Europe Energy Crisis | Joe Biden | Inflation Reduction Act | Ursula von der Leyen | Latest News | Firstpost

#exxonmobil #europeanunion #usa #joebiden #ursulavonderleyen #inflationreductionact #america #oil #latestnews #firstpost | n18oc_world

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Music Credits: JHC BEATS – MALIANTEO TYPE BEAT | No Copyright Trap

JHC BEATS
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Liked on YouTube: Pakistan Economic Woes: Top car companies Pak Suzuki, Indus Motors halt production for up to 10 days

Amid a grim economic outlook in Pakistan, car manufacturing companies are announcing production halts. The latest to join the trail is the Pak Suzuki , Indus Motors, citing a shortage of inventory level.

#pakistan #paksuzuki #indusmotors

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WION The World is One News, examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to the politics of the world. People are tired of biased reportage and we stand for a globalised united world. So for us the World is truly One.

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Liked on YouTube: Turkey’s vow to become the gas hub of Europe leaves Biden in a state of insomnia

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Are Signal, Whatsapp, Telegram, Protonmail, Tutanota safe to use?

Some people jump to the conclusion that simply because an app is encrypted, it is secure for you to use. I’ll talk about how many popular apps like Whatsapp that are thought to be safe because of encryption are actually full of risks because the people who say they are safe haven’t done much research into the apps’ weaknesses.

An item referred to as a relationship map is the fundamental problem. Because of how each of these apps is used, this problem can make it possible to find out everything about everyone in a chat, including their profiles. I’ll describe how this happens and how knowing how it operates is a crucial component of what the intelligence community refers to as SIGINT (Signals Intelligence).

Watch the video to discover more about this simple puzzle that will make you think more clearly.

DON’T USE GMAIL unless you make these 5 Critical Security Changes

Gmail security is not difficult, but it does need action! Learn how by following these five Gmail security guidelines step by step.

With a strong password, two-factor authentication, and a thorough review of all trusted devices and third-party permissions, you can make sure that Gmail is as safe as possible. These are really simple tasks, and the following guide will show you exactly how to complete them.

Due to the fact that you share so much information on the website, protecting your Google account is crucial. If your password is stolen and someone gains access to your account, they can easily browse through your files, pictures, and documents. Finally, this person will have complete access to all of your emails and can even send some tricky ones.